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Diflucan (fluconazole) is a medication specially intended for the treatment of infections caused by different types of fungi. Diflucan is usually taken once a day unless otherwise recommended by your health care provider. How long you will need to be taking this medicine depends on your condition and the way your body responds to the treatment. Some medical conditions you have may affect the dose you are prescribed - the following ones are known to do that: heart disease, AIDS, liver disease., irregular heartbeat, kidney disease, and cancer. Make sure your health care provider is always aware of the fact you are using some other medications, such as diuretics, amiodarone, disopyramide, rifampin, benzodiazepines, valproic acid, rifabutin, oral medicines for diabetes, phenytoin, erythromycin, cyclosporine, anticoagulants, astemizole, clopidogrel, thioridazine, theophylline, isoniazid, or quinidine. Interactions have been reported between Diflucan and the drugs mentioned, so you will need to ask your health care provider how to make sure you can benefit from both your treatments.